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Animal Sciences and Industry

Publications

 L.K.Mamedova, K.Yuan, A.N.Laudick, S.D. Fleming,D.G. Mashek and B. J. Bradford. 2013. Toll-like receptor 4 signaling is required for induction of gluconeogenic gene expression by palmitate in human hepatic carcinoma cells. J Nutr Biochem 24(8):1499-507.

 C.R.Mullins, L.K. Mamedova, A.J. Carpenter, Y. Ying,  M.S. Allen, I. Yoon, B.J.  Bradford. 2013. Analysis of rumen microbial populations in lactating dairy cattle fed diets varying in carbohydrate profiles and Saccharomyces cerevisiae fermentation product. J Dairy Sci. 96(9):5872-81.

  J.K. Farney, L.K. Mamedova,  J.F. Coetzee, B. KuKanich, L.M. Sordillo, S.K. Stoakes, J.E. Minton, L.C. Hollis,  B.J. Bradford. 2013. Anti-inflammatory salicylate treatment alters the metabolic adaptations to lactation in dairy cattle. Am J Physiol Regul Integr Comp Physiol.305(2):R110-7.

C.R. Mullins, L. K. Mamedova, M. J. Brouk, C. E. Moore, H. B. Green, K. L. Perfield, J. F. Smith, J. P. Harner, and B. J. Bradford. 2012. Effects of monensin on metabolic parameters, feeding behavior, and productivity of transition dairy cows. J Dairy Sci. 95(3):1323-36.

P. Rezamand, J. S. Watts, K. M. Hunt, B. J. Bradford, L. K. Mamedova, and S. D. Morey. 2012. Bovine hepatic and adipose retinol-binding protein gene expression and relationship with tumor necrosis factor-alpha. J Dairy Sci. 95(12):7097-104.

Titgemeyer, E.C., K. S. Spivey, L. K. Mamedova, and B. J. Bradford. 2011. Effects of pharmacological amounts of nicotinic acid on lipolysis and feed intake in cattle. Int. J. Dairy Sci. 6:134-141.
Titgemeyer, E.C., L.K. Mamedova, K.S. Spivey, J.K. Farney, and B.J. Bradford. 2011. An unusual distribution of the niacin receptor in cattle. J. Dairy Sci. 94:4962-4967.

L. Mamedova, B. Bradford, K. Robbins, and B. Johnson, 2008. Tissue expression of fasting-induced adipocyte factor in cattle. FASEB J. 22: 1116.1112

L.K. Mamedova, R. Wang, P. Besada, B. Liang, K. A. Jacobson. Attenuation of Apoptosis in vitro and Ischemia/Reperfusion Injury in vivo in Mouse Skeletal Muscle by P2Y6 Receptor Activation Pharmacological Research. 2008; 58:232-239

K.A. Jacobson, S.Costanzi, J. Bhalchandra, P. Besada, D.H. Shin, H.J. Ko, A. Ivanov, L. Mamedova. Agonists and antagonists for P2 receptors. Purinergic signalling in neuronglia interactions. Wiley, Chichester. Novartis Foundation Symposium UK. 2006; 276:58-72

N. Erkasap, M. Ikizler, V. Shneyvays, T. Zinman, L.K. Mamedova, R. Uyar, A. Shainberg. Leptin protects the cardiac myocyte cultures from hypoxic damage. Life sci. 2006; 78:1098-1102

P. Besada, L.K. Mamedova, K.K. Palaniappan, Z-G-Gao, B.V. Joshi, L.S. Jeong, M.M. Civan, K.A. Jacobson. Nucleoside prodrugs of A3 adenosine receptor agonists and antagonists. Col. Czechoslovak Chem. Com. 2006; 912-28

Z.G. Gao, H.T. Duong, T. Sonin, S.K. Kim, P. Rompaey, S. Calenbergh, L. Mamedova, L.S. Jeong, H.O. Kim, M. J. Kim, A.Y. Kim, B.T. Liang, K.A. Jacobson. Orthogonal activation of the reengineered A3 adenosine receptor (neoceptor) using tailored nucleoside agonists. J. Med. Chem. 2006; 49:2689 -2702

L.K. Mamedova, Z-G Gao and K.A. Jacobson. ADP Regulates Death and Survival in Astrocytes by Activating P2Y1 and P2Y12 Receptors. Biochem. Pharmacol. 2006; 72:1031-1041

L. Mamedova, V. Capra, M.R. Accomazo, Z.G. Gao, S. Ferrario, M. Fumagalli, M.P. Abbracchio, G.E. Rovati, K.A. Jacobson. CysLT1 leukotriene receptor antagonists inhibit the effects of nucleotides acting at P2Y receptors. Biochem. Pharmacol. 2005; 71:115-125

K.A. Jacobson, L. Mamedova, J.V. Bhalchandra, P. Besada, S. Costanzi. Molecular Recognition at Adenine Nucleotide (P2) Receptors in Platelets Seminars in Thrombosis and Hemostasis. 2005; 31:N2:205-216

P. Besada, L. Mamedova, C.J. Thomas, S. Costanzi and K.A. Jacobson. Design and synthesis of new bicyclic diketopiperazines as scaffolds for receptor probes of structurally diverse functionality. Org. Biomol. Chem. 2005; 3:2016-2025

S. Costanzi, J. Bhalchandra, S.. Maddileti, L. Mamedova, M.J. Gonzalez-Moa, V.E. Marquez, T.K. Harden, K.A. Jacobson. Human P2Y6 receptor: Molecular modeling leads to the rational design of a novel agonist based on a unique conformational preference. J. Med. Chem. 2005; 48:8108-8111

Y.C. Kim, J.S. Lee, K. Sak, F. Marteau, L. Mamedova, J.M. Boeynaems, K.A. Jacobson. Synthesis of pyrodoxal phosphate derivatives with antagonist activity at the P2Y13 receptor. Biochem. Pharmacol. 2005; 70:266-274

V. Shneyvays, D. Leshem, T. Zinman, L.K. Mamedova, KA. Jacobson, A. Shainberg. Role of adenosine A1 and A3 receptors in regulation of cardiomyocyte homeostasis following mitochondrial respiratory chain injury. Am. J. Physiol. Heart Circ. Physiol. 2005; 288:2792-2801

L.K. Mamedova, B.V. JoshiZ-G Gao, I. Kügelgen, K.A. Jacobson. Diisothiocyanate derivatives as potent, noncompetitive inhibitors of P2Y6 nucleotide receptors. Biochem. Pharmacol. 2004; 67:1763-1770

S. Costanzi, L. Mamedova, Z. Gao and K.A. Jacobson. Architecture of P2Y nucleotide receptors: structural comparison based on sequence analysis, Mutagenesis, and homology modeling. J. Med. Chem. 2004; 47(22):5393-5404

Z-G. Gao, L. Mamedova, S. Tchilibon, A.S. Gross, K.A. Jacobson. 2,2-Pyridylisatogen tosylate antagonizes P2Y1 receptor signaling without affecting nucleotide binding. Biochem. Pharmacol. 2004; 68:231-237

N. tribulova, V. Shneyvays, L.K. Mamedova, S. Moshel, A.Shainberg, M. Manoach, Weismann, S. Kostin. Enhanced connexin-43 and α-sarcomeric actin expression in cultured heart myocytes exposed to triiodo-L-thyronine. J. Mol. Hist. 2004; 35:63-470

L.K. Mamedova, V.Shneyvays, A.Katz and A. Shainberg. Mechanism of glycogen supercompensation in rat skeletal muscle cultures: Mol. Cell. Biochem. 2004; 250:11-19

Z-G.Gao, L.K. Mamedova, P. Chen, K.A. Jacobson. 2-Substituted adeno-sinederivatives: Affinity and efficacy are four subtypes of human adenosine receptors. Biochem. Pharmacol. 2004; 68:1985-1993

Z. Gao, L. Jeong, H. Moon, H. Kim, W. Choi, D. Shin, E. Elhalem, M. Comin, N. Melman, L. Mamedova, A. Gross, J. Rodriguez, K. Jacobson. Structural deterinants of efficacy at A3 adenosine receptors. Modification of the ribose moiety. Biochem. Pharmacol. 2004; 67:893-901

A. Vigoda, L.K. Mamedova, V. Shneyvays, A. Katz and A. Shainberg. Glycogen metabolism in rat heart muscle cultures after hypoxia. Mol. Cell. Biochem. 2003; 254:311-318